7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one

Classification: Tolvaptan

Compound English name: 7-Chloro-1,2,3,4-Tetrahydro-Benzo[B]Azepin-5-One

CAS No.: 160129-45-3

Molecular formula: C10H10ClNO

Molecular weight: 195.645

Exact quality: 195.045

LogP: 2.8664

PSA: 29.1

Refractive index: 1.562

Steam pressure: 2.9E-05mmHg at 25°C

Density: 1.234 g/cm3

Boiling point: 356.5oC at 760 mmHg

Product Description

Description


7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one is an intermediate in the synthesis of 7-Chloro-5-hydroxy-1-[2-methyl-4-(2-methylbenzoyl-amino)benzoyl]-2,3,4,5 -tetrahydro-1H-1-benzazepine (OPC-41061), an orally active nonpeptide arginine vasopressin V2 receptor antagonist




Basic Info

Chemical Name

7-Chloro-1,2,3,4-Tetrahydro-Benzo[B]Azepin-5-One

Synonyms

7-Chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one;7-CHLORO-1,2,3,4-TETRAHYDRO-BENZO[B]AZEPIN-5-ONE;7-Chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one;7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one;

CAS No.

160129-45-3

Molecular Formula

C10H10ClNO

Molecular Weight

195.64500

PSA

29.10000

LogP

2.86640





Properties

Density

1.234 g/cm3

Boiling Point

356.5ºC at 760 mmHg

Refractive Index

1.562

Vapor Pressure

2.9E-05mmHg at 25°C




Safety Info


HS Code

2933990090


Company Profile

Jinan Xinnuo Pharmaceutical Technology Co., Ltd. is a high-tech enterprise specializing in the production of pharmaceutical intermediates. The company has been engaged in the research, development and production of chemical intermediates for more than 10 years. It integrates research, development, production, import and export trade, strong technical force, advanced testing methods, strong research and development capabilities and superb synthetic technology. It is an incubator of Jinan Pharmaceutical Valley. Committed to gout, nutrition, anti-cancer, anti-depression, anti-age dementia and drug synthesis in the cardiovascular and cerebrovascular fields. The products are mainly exported, and the products are exported to more than 40 countries and regions such as Southeast Asia, South America and Eastern Europe.

The company has a complete quality assurance system and strong scientific research and innovation strength. Every year, new market-oriented and high-tech synthetic drugs are launched. We are willing to provide you with quality products and competitive prices. Efficient service.

Products
Name
Contact information
E-mail
Message

Copyright: Jinan Xinnuo Pharmaceutical Technology Co., Ltd. All rights reserved.   Powered by:MRWL