(6R,7R)-Benzhydryl3-hydroxy-8-oxo-7- (2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylate

Classification: Ceftaroline

English name: (6R,7R)-3-Hydroxy-8-oxo-7-[(phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenyl Methyl ester

CAS No.: 54639-48-4

Molecular formula: C28H24N2O5S

Molecular weight: 500.566

Exact quality: 500.141

LogP: 4.0602

PSA: 121.24

Refractive index: 1.725

Product Description

Description


3(6R,7R)--Hydroxy-8-oxo-7-[(2-phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Diphenylmethyl Ester is a useful synthetic intermediate. It was used to prepare cephalosporin-derived inhibitors. It can also be used to synthesize Ceftaroline Fosamil which is a cephalosporin antibiotic.




Basic Info

Chemical Name

(6R,7R)-3-Hydroxy-8-oxo-7-[(phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenyl methyl ester

Synonyms

GHYH;3-hydroxycephem;3-Oh;7-PHENYL ACETAMIDO-3-HYDROXY-3-CEPHEM-4-CARBOXYLIC ACID DIPHENYLMETHYL ESTER,3-OH;7-PHENYLACETAMIDE-3-HYDROXY-3-CEPHEM-4-CARBOXYLIC ACID DIPHENYLMETHYL ESTER;3-OH: 7-PHENYL ACETAMIDO-3-HYDROXY-3-CEPHEM-4-CARBOXYLIC ACID DIPHENYLMETHYL ESTER;7-PHENYL ACETAMIDO-3-HYDROXY-3-CEPHEM-4-CARBOXYLIC ACID DIPHENYLMETHYL ESTER;

CAS No.

54639-48-4

Molecular Formula

C28H24N2O5S

Molecular Weight

500.56600

PSA

121.24000

LogP

4.06020





Properties


Appearance & Physical State

White or off-white crysalline powder

Density

1.6 g/cm3

Boiling Point

715.5ºC at 760 mmHg

Flash Point

386.5ºC

Refractive Index

1.725





Safety Info


HS Code

2941905990



Company Profile

Jinan Xinnuo Pharmaceutical Technology Co., Ltd. is a high-tech enterprise specializing in the production of pharmaceutical intermediates. The company has been engaged in the research, development and production of chemical intermediates for more than 10 years. It integrates research, development, production, import and export trade, strong technical force, advanced testing methods, strong research and development capabilities and superb synthetic technology. It is an incubator of Jinan Pharmaceutical Valley. Committed to gout, nutrition, anti-cancer, anti-depression, anti-age dementia and drug synthesis in the cardiovascular and cerebrovascular fields. The products are mainly exported, and the products are exported to more than 40 countries and regions such as Southeast Asia, South America and Eastern Europe.

The company has a complete quality assurance system and strong scientific research and innovation strength. Every year, new market-oriented and high-tech synthetic drugs are launched. We are willing to provide you with quality products and competitive prices. Efficient service.

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